Related Experiment Video
Updated: May 17, 2026

04:11
Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
Comparison of acute viral hepatitis data quality using two methodologies, 2005-2007.
Kashif Iqbal1, R Monina Klevens, Ruth Jiles
1Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of Viral Hepatitis, Atlanta, GA 30333, USA. kai9@cdc.gov
Public Health Reports (Washington, D.C. : 1974)
|November 2, 2012
Summary
Funding for viral hepatitis surveillance significantly improves data quality and timeliness. Emerging Infections Program (EIP) sites provided more complete demographic and risk information compared to non-funded sites.
Area of Science:
- Public Health Surveillance
- Infectious Disease Epidemiology
- Viral Hepatitis Research
Background:
- Effective surveillance for acute viral hepatitis (A, B, C) is crucial for public health response.
- Data quality and reporting timeliness impact the ability to monitor disease trends and implement interventions.
- The Centers for Disease Control and Prevention (CDC) Emerging Infections Program (EIP) funds specific surveillance activities.
Purpose of the Study:
- To compare the quality of acute viral hepatitis surveillance data between CDC-funded EIP sites and non-funded National Electronic Disease Surveillance System (NEDSS)-based states (NBS) sites.
- To assess differences in data completeness, adherence to case definitions, and reporting timeliness.
Main Methods:
- Descriptive analysis of acute hepatitis A, B, and C cases reported between 2005-2007.
- Comparison of data completeness (demographics, risk behaviors), adherence to CDC/CSTE case definitions, and reporting timeliness between EIP and NBS sites.
Main Results:
- EIP sites reported more complete race/ethnicity data and a higher likelihood of including risk behavior information compared to NBS sites.
- Case reports from EIP sites were more likely to meet the CDC/CSTE case definition for acute hepatitis A, B, and C.
- EIP sites demonstrated more timely reporting of cases to health departments than NBS sites, although the acute hepatitis C case definition posed challenges for both.
Conclusions:
- Data quality and timeliness in acute viral hepatitis surveillance are superior in CDC-funded EIP sites compared to non-funded NBS sites.
- Financial support for surveillance activities is essential for generating high-quality data necessary for informed public health decision-making and response.
Related Concept Videos
Viral Hepatitis I: Introduction
Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Hepatitis
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
