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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: May 17, 2026

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

[Cutaneous malignant melanoma: one single disease ?].

G E Piérard¹, C Piérard-Franchimont, T Hermanns-Lê

¹Université de Liège et Besançon, France.

Revue Medicale De Liege

|November 3, 2012

Summary

Malignant melanoma, a dreaded skin cancer, is not a single disease. Different melanoma types have unique origins and prognoses, requiring individualized patient management and information.

Area of Science:

Oncology
Dermatology
Pathology

Context:

Malignant melanoma is widely perceived as a singular, severe skin cancer.
Public and media understanding often overlooks the heterogeneity of this disease.

Purpose:

To highlight the distinct pathological subtypes of malignant melanoma.
To emphasize the importance of personalized treatment strategies based on melanoma type.

Summary:

Clinical presentation, histopathology, and molecular genetics reveal that malignant melanoma comprises diverse subtypes.
These subtypes originate differently and possess distinct prognostic trajectories.
Recognizing these differences is crucial for effective patient care.

Impact:

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Promotes a more nuanced understanding of malignant melanoma beyond a monolithic view.
Advocates for tailored management plans and patient education specific to individual melanoma types.
Improves potential patient outcomes through personalized oncological and dermatological approaches.