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Updated: May 17, 2026

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Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
Breast-conserving surgery in breast cancer
T S Tenea Cojan1, C D Vidrighin, M Ciobanu
1Department of General Surgery, C F Clinical Hospital, Craiova, Romania. doctortts@yahoo.com
Summary
Breast-conserving surgery followed by irradiation offers reliable breast cancer treatment outcomes comparable to mastectomies. This approach prioritizes patient well-being and cosmetic results, demonstrating the efficacy of breast conserving therapy.
Area of Science:
- Oncology
- Surgical Oncology
- Radiotherapy
Background:
- Modern breast cancer treatment increasingly utilizes breast-conserving surgery (BCS) for early-stage disease.
- BCS aims for radical tumor removal while preserving breast tissue.
Purpose of the Study:
- To evaluate the long-term efficacy and applicability of BCS with adjuvant radiotherapy.
- To highlight the oncological and cosmetic outcomes of BCS in a prospective setting.
Main Methods:
- Prospective monitoring of 303 patients undergoing BCS over 16 years.
- Protocol included tumor excision with clear margins, axillary lymph node dissection, and postoperative irradiation.
- Adjuvant chemotherapy was administered based on clinical and pathological factors.
Main Results:
- Low local recurrence rate of 3.96% (12 cases) and 2 deaths from cancer progression.
- Oncological results were comparable to radical mastectomy outcomes.
- Cosmetic outcomes were satisfactory and dependent on tumor and breast size.
Conclusions:
- Breast-conserving surgery followed by breast irradiation is a reliable and effective treatment for breast cancer.
- BCS achieves oncological safety comparable to mastectomy while offering improved cosmetic results.
- Long-term monitoring supports the importance and applicability of breast conserving therapy.

