Related Experiment Video
Updated: May 17, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Cerebral hemorrhage in a mechanically ventilated asthmatic child: multifactorial mechanisms]
M Baravalle1, F Michel, B Tosello
1Unité de réanimation pédiatrique et néonatale et unité de brûlés pédiatriques, CHU Nord, Assistance publique-Hôpitaux de Marseille, chemin des Bourrely, Marseille cedex 20, France.
Insights
A pediatric patient with severe asthma experienced a brain hemorrhage during mechanical ventilation in the pediatric intensive care unit. This case highlights a rare neurological complication of acute respiratory distress in children.
Area of Science:
- Pediatric Critical Care Medicine
- Pediatric Neurology
- Respiratory Medicine
Background:
- Acute status asthmaticus is a severe form of asthma exacerbation.
- Mechanical ventilation is a life-saving intervention for respiratory failure in pediatric patients.
- Neurological complications can arise in critically ill children, particularly those with severe respiratory illness.
Observation:
- A 7-year-old boy with acute status asthmaticus required mechanical ventilation in the pediatric intensive care unit.
- During his illness, the patient developed a brain hemorrhage.
- The neurological complication occurred in the context of severe respiratory distress and intensive care management.
Findings:
- The case presents a rare instance of brain hemorrhage in a child with acute status asthmaticus.
- Potential mechanisms linking severe asthma, mechanical ventilation, and intracranial bleeding are explored.
- This suggests a possible association between respiratory failure management and cerebrovascular events in pediatric patients.
Implications:
- Understanding the pathophysiology of neurological complications in severe asthma is crucial for pediatric critical care.
- This case may inform strategies for monitoring and managing critically ill children with respiratory conditions.
- Further research into the neurovascular effects of mechanical ventilation in pediatric respiratory failure is warranted.
Abstract:
We report the case of a 7-year-old boy with acute status asthmaticus requiring mechanic ventilation in the pediatric intensive care unit. He developed a brain hemorrhage during the course of his illness. We discuss the mechanisms that may have precipitated this neurological complication.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology

