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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

[Clinical application of the 3-dimensional speckle tracking imaging in coronary artery disease]

Wenhui Zhu1, Qin Meng, Jidong Xiao

  • 1Department of Ultrasound, Central South University, Changsha, China.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|November 3, 2012
PubMed

Insights

Three-dimensional speckle tracking imaging (3D-STI) accurately assesses left ventricular systolic function in coronary artery disease patients. This technique quantifies function and reflects stenosis severity, aiding diagnosis.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Coronary artery disease (CAD) diagnosis relies on assessing left ventricular (LV) systolic function.
  • Conventional echocardiography and wall motion score index (WMSI) have limitations in quantitative evaluation.
  • Three-dimensional speckle tracking imaging (3D-STI) offers advanced capabilities for cardiac function assessment.

Purpose of the Study:

  • To evaluate the clinical diagnostic utility of 3D-STI in coronary artery disease.
  • To quantitatively assess LV segmental and global systolic function using 3D-STI.
  • To correlate 3D-STI parameters with the severity of coronary artery stenosis.

Main Methods:

  • 150 patients with suspected CAD were categorized into five groups based on coronary angiography results.
  • Gensini score and WMSI were calculated for each patient.
  • 3D-STI was employed to measure LV segmental and global systolic function parameters.

Main Results:

  • Ejection fraction was reduced in the multivessel group compared to controls.
  • Peak systolic 3D strains were diminished in all segments for the multivessel group and in main supply segments for other groups.
  • Global 3D strain (G3DS) showed a strong negative correlation with Gensini score (r = -0.76, P<0.01).

Conclusions:

  • 3D-STI provides quantitative assessment of LV segmental and global systolic function.
  • 3D-STI effectively reflects the extent of coronary artery stenosis in CAD patients.
  • 3D-STI demonstrates high sensitivity and accuracy for diagnosing coronary artery disease.
Abstract

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