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Automated segmentation algorithm for detection of changes in vaginal epithelial morphology using optical coherence

Shahab Chitchian1, Kathleen L Vincent, Gracie Vargas

  • 1University of Texas Medical Branch, Center for Biomedical Engineering, Galveston, Texas 77555, USA.

Journal of Biomedical Optics
|November 3, 2012
PubMed
Summary

Optical coherence tomography (OCT) noninvasively assesses topical microbicide toxicity by monitoring vaginal epithelial integrity. A new algorithm accurately differentiates healthy and damaged tissue, aiding microbicide safety evaluations.

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