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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

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The diabetic neuropathies: practical and rational therapy.

J Robinson Singleton¹, A Gordon Smith

¹University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.

Seminars in Neurology

|November 3, 2012

Summary

Diabetic neuropathies, including distal symmetric polyneuropathy (DSP), are common. This review covers treatments for improving hyperglycemia and neuropathic pain, and preventing complications.

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Area of Science:

Neurology
Endocrinology
Metabolic Diseases

Background:

Diabetes mellitus is linked to diverse chronic and acute neuropathies.
Distal symmetric polyneuropathy (DSP) is the most prevalent form, significantly impacting patient quality of life.

Purpose of the Study:

To summarize clinical features of common diabetic neuropathies.
To review available and investigational therapies for diabetic neuropathies, with a focus on DSP.

Main Methods:

Literature review of clinical features and therapeutic strategies for diabetic neuropathies.
Categorization of DSP treatments into four themes: metabolic control, disease-modifying pharmacotherapy, pain management, and complication prevention.

Main Results:

DSP management involves improving hyperglycemia, insulin resistance, obesity, and dyslipidemia.
Pharmacologic therapies targeting known pathophysiology are under investigation.
Symptomatic pain relief and prevention of complications like ulcers and falls are crucial.

Conclusions:

Comprehensive management of diabetic neuropathies requires addressing metabolic factors, exploring disease-modifying treatments, managing pain, and preventing secondary complications.
The article provides an overview of current and emerging therapeutic approaches for diabetic neuropathies.