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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Drug Dosing: Infants and Children

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Guidelines for Nursing Documentation I01:30

Guidelines for Nursing Documentation I

Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:  
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
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Guidelines and Strategies for Safe Computer Charting

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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Systematic steps to diminish multi-fold medication errors in neonates.

Joaquim M B Pinheiro1, Amy L Mitchell, Timothy S Lesar

  • 1Department of Pediatrics, Albany Medical College, Albany, New York.

The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Multiple-of-dose medication errors are frequent in neonatal intensive care units (NICUs). Implementing simple, inexpensive techniques can systematically reduce these errors, improving patient safety in neonatal care.

Keywords:
medication errorsneonates

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Area of Science:

  • Neonatal intensive care
  • Pharmacology
  • Patient safety

Background:

  • Multiple-of-dose medication errors are common in neonatal intensive care units (NICUs).
  • Patient fragility in NICUs heightens the risk of adverse outcomes from medication errors.
  • Errors can occur at any stage, from ordering to administration.

Purpose of the Study:

  • To describe techniques for reducing medication errors in a NICU setting.
  • To present practical strategies for avoiding decimal and multiple-dosing errors.
  • To highlight the potential for integrating these techniques into computerized systems.

Main Methods:

  • Implementation of simple, inexpensive technologies for information and automation.
  • Standardization and simplification of medication-related processes.
  • Systematic application of principles to prevent dosing errors.

Main Results:

  • The described techniques were implemented in a NICU setting.
  • These methods focus on error reduction throughout the medication process.
  • The approach aims to decrease the incidence of undetected human error.

Conclusions:

  • Simple, adaptable techniques can significantly reduce medication errors in NICUs.
  • These methods can be integrated into existing or new computerized order entry systems.
  • Standardization and simplification are key to enhancing safety in neonatal medication management.