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Related Concept Videos

Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Updated: May 17, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Managing asthma: past, present, and future.

Miles Weinberger1

  • 1Department of Pediatrics, Director, Pediatric Allergy & Pulmonary Division, University of Iowa College of Medicine, Iowa City, Iowa.

The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
|November 3, 2012
PubMed
Summary

Modern asthma pharmacotherapy evolved from early bronchodilators to inhaled corticosteroids, offering effective chronic asthma management. Newer treatments include monoclonal antibodies targeting IgE and interleukins, improving outcomes for allergic and viral-exacerbated asthma.

Keywords:
asthma

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Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Pharmacology

Background:

  • Asthma management has evolved significantly over two millennia.
  • Early 20th-century advancements introduced epinephrine for acute asthma relief.
  • Corticosteroids, introduced 50 years ago, revolutionized anti-inflammatory treatment.

Purpose of the Study:

  • To review the historical development and current advancements in asthma pharmacotherapy.
  • To highlight the efficacy of inhaled corticosteroids as a cornerstone of chronic asthma management.
  • To explore emerging therapies for allergic and viral-induced asthma exacerbations.

Main Methods:

  • Review of historical medical literature on asthma treatments.
  • Analysis of the pharmacological mechanisms of bronchodilators and corticosteroids.
  • Examination of novel biologic agents and investigational therapies.

Main Results:

  • Inhaled corticosteroids are highly effective for chronic asthma, offering topical anti-inflammatory effects with minimal systemic absorption.
  • Combination therapy with theophylline or long-acting beta2 agonists enhances inhaled corticosteroid efficacy.
  • Monoclonal antibodies targeting immunoglobulin E (IgE) represent a new frontier for allergic asthma treatment.

Conclusions:

  • Inhaled corticosteroids are the most effective monotherapy for chronic asthma.
  • Emerging biologics, including monoclonal antibodies, show promise for managing complex asthma phenotypes.
  • Preventative strategies targeting viral infections may reduce asthma exacerbations.