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Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
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Related Experiment Video

Updated: May 17, 2026

Collection of Alfalfa Root Exudates to Study the Impact of Di(2-ethylhexyl) Phthalate on Metabolite Production
06:46

Collection of Alfalfa Root Exudates to Study the Impact of Di(2-ethylhexyl) Phthalate on Metabolite Production

Published on: June 2, 2023

Di(2-ethylhexyl)phthalate (DEHP).

Arthur A Strauss1

  • 1Neonatal Intensive Care Unit, Miller Children's Hospital, Long Beach, California and Department of Pediatrics, University of California, Irvine, California.

The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Di(2-ethylhexyl) phthalate (DEHP) can leach from medical devices into patients. This review updates concerns regarding DEHP

Keywords:
DEHPMEHPphthalates

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Area of Science:

  • Toxicology
  • Environmental Health
  • Clinical Medicine

Background:

  • Di(2-ethylhexyl) phthalate (DEHP) is a chemical plasticizer.
  • DEHP is soluble in blood and body fluids.
  • Concerns exist regarding DEHP leaching from medical devices into patients.

Purpose of the Study:

  • To provide an update on DEHP's status as a potential reproductive toxin.
  • To discuss implications for high-risk populations, particularly neonates.
  • To explore the precautionary principle in relation to DEHP exposure.

Main Methods:

  • Literature review and synthesis of current research on DEHP.
  • Analysis of DEHP's toxicological profile, focusing on reproductive effects.
  • Discussion of clinical relevance and patient exposure routes.

Main Results:

  • DEHP remains a substance of concern due to its leaching from medical devices.
  • Emerging evidence highlights DEHP's potential as a reproductive toxin.
  • Neonates are identified as a particularly vulnerable population.

Conclusions:

  • Continued vigilance and research are necessary regarding DEHP exposure.
  • The precautionary principle should guide healthcare professionals' approach to DEHP.
  • Minimizing patient exposure to DEHP is crucial, especially in neonatal care.