Microbiology and Management of Pediatric Liver Abscesses: Two Cases Caused by Streptococcus anginosus Group

Michael Cellucci1, Erin Simon, Stephen Eppes

  • 1Diagnostic Referral Division, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, De 19803, USA.

Insights

Pyogenic liver abscesses are rare in children. This study discusses two cases caused by Streptococcus anginosus group bacteria, highlighting their microbiology, management, and treatment in pediatric patients.

Area of Science:

  • Pediatric Infectious Diseases
  • Hepatology
  • Microbiology

Background:

  • Pyogenic liver abscesses are uncommon in developed countries, particularly in pediatric patients.
  • The Streptococcus anginosus group is a rare but significant cause of pyogenic liver abscesses.

Purpose of the Study:

  • To report two cases of pediatric pyogenic liver abscesses caused by the Streptococcus anginosus group.
  • To discuss the microbiology, clinical presentation, and management of these infections in children.

Main Methods:

  • Case report presentation of two pediatric patients with pyogenic liver abscesses.
  • Review of the microbiology of Streptococcus anginosus group organisms.
  • Discussion of current management and treatment strategies for pediatric liver abscesses.

Main Results:

  • Two previously healthy male children presented with fever and abdominal pain.
  • Both cases were diagnosed with pyogenic liver abscesses attributed to the Streptococcus anginosus group.
  • The study reviews the specific characteristics and treatment outcomes for these rare pediatric cases.

Conclusions:

  • The Streptococcus anginosus group can cause pyogenic liver abscesses in otherwise healthy children.
  • Prompt diagnosis and appropriate antimicrobial therapy are crucial for successful management.
  • Further research into the specific virulence factors and optimal treatment protocols for pediatric S. anginosus liver abscesses is warranted.

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