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Purely cortical anaplastic ependymoma.
Flávio Ramalho Romero1, Marco Antônio Zanini, Luis Gustavo Ducati
1Division of Neurosurgery, Botucatu Medical School, São Paulo State University (UNESP), 18618-970 Botucatu, SP, Brazil ; Departamento de Neurologia, Psiquiatria e Psicologia, (UNESP), Distrito de Rubião Júnior s/n, 18618-970 Botucatu, SP, Brazil ; Hospital das Clínicas, São Paulo State University (UNESP), 18618-970 Botucatu, SP, Brazil.
This study reports an extremely rare case of a pure cortical ectopic anaplastic ependymoma, a type of brain tumor originating outside the brain
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Ependymomas are glial tumors originating from ependymal cells lining the brain's ventricles and spinal cord's central canal.
- Ectopic ependymomas are rare, occurring outside these typical locations, with fewer than 15 reported cases.
- Anaplastic ependymomas are a high-grade subtype, and ectopic anaplastic ependymomas are exceptionally uncommon, with fewer than five previously documented.
Purpose of the Study:
- To report a unique case of a pure cortical ectopic anaplastic ependymoma.
- To contribute to the limited literature on ectopic and anaplastic ependymomas.
Main Methods:
- Case report detailing clinical presentation, neuroimaging findings, and histopathological analysis.
- Review of relevant literature on ectopic and anaplastic ependymomas.
Main Results:
- A rare instance of a pure cortical ectopic anaplastic ependymoma was identified and characterized.
- The tumor presented as a distinct entity within the cerebral cortex, separate from ventricular structures.
Conclusions:
- This case highlights the diverse and rare presentations of ependymomas.
- Further research and case accumulation are needed to understand the behavior and optimal management of ectopic anaplastic ependymomas.
