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Updated: May 17, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Clinical, radiological and surgical correlation in cancers of the paranasal sinuses
D A Tandon1, A Gairola, S Bahadur
1Dept. of Otolarynglogy and Head and Neck Surgery, All India Institute of Medical Sciences, 110029 New Delhi.
Abstract:
Clinical, radiological and CT findings for each adjacent subsite were tabulated and compared in 25 consecutive cases undergoing surgery for malignant lesions of the maxillo-ethmoid complex. It was found that tumour extensions into nose, palate, cheek and orbit were identified correctly in a high proportion of cases clinically and radiologically. Posterior extensions into infratemporal or pterygopalatine fossae were evident clinically in only one out of 5 cases. Clinical assessment failed to detect orbital invasion in 3 out of 7 cases, while CT missed orbital periosteal involvement in one case. CT overestimated spheno-ethmoidal extensions of tumour in 44% (8/18) cases.
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