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Related Concept Videos

Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Allergic Reactions02:06

Allergic Reactions

Overview

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Updated: May 17, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Cryosurgery in allergic rhinitis.

S Varshney1, K Chandra

  • 1M.I.G.-60, A.D.A., Colony, Ramghat Road, 202 001 Aligargh, U.P.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Cryosurgery offers an effective treatment for chronic allergic rhinitis, providing relief for nasal allergy symptoms. This study shows significant improvement in many patients unresponsive to conventional therapies.

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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Otolaryngology
  • Allergology
  • Surgical Innovation

Background:

  • Chronic allergic rhinitis presents significant challenges in treatment.
  • Conventional therapies often lead to patient frustration due to persistent symptoms.
  • Hypertrophied inferior turbinates and autonomic innervation are key factors in allergic rhinitis pathology.

Purpose of the Study:

  • To evaluate cryosurgery as an alternative treatment for chronic allergic rhinitis.
  • To assess the efficacy of cryosurgery in debulking inferior turbinates and altering autonomic innervation.
  • To determine the long-term relief provided by cryosurgery for allergic rhinitis.

Main Methods:

  • Cryosurgery was performed using a cryoprobe at -90°C on 104 patients with allergic rhinitis.
  • The procedure targets hypertrophied inferior turbinates and autonomic nerve supply.
  • Patient outcomes were evaluated over a 3-6 month follow-up period.

Main Results:

  • Complete symptom relief (rhinorrhoea, nasal obstruction, sneezing) was achieved in 40.4% of patients.
  • Moderate improvement was observed in 30.87% of cases, with significant relief in two key symptoms.
  • Satisfactory results were noted in 19.27% of patients, indicating overall improvement.
  • Only 9.67% of patients reported no improvement after cryosurgery.

Conclusions:

  • Cryosurgery demonstrates effectiveness as a treatment modality for chronic allergic rhinitis.
  • The procedure offers a viable alternative for patients experiencing persistent symptoms.
  • Cryosurgery provides a potential for permanent relief in managing allergic rhinitis.