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Related Concept Videos

Diabetes Insipidus I: Introduction01:29

Diabetes Insipidus I: Introduction

Definition Diabetes insipidus is a disorder marked by the production of large amounts of dilute urine because of impaired vasopressin production, release, or kidney response. The lack of effective vasopressin action limits water reabsorption in the renal collecting ducts, which leads to excessive urinary water loss and intense thirst.Clinical PresentationIndividuals with diabetes insipidus report persistent thirst and very high urine output. In severe cases, fluid intake can reach up to 20...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Equilibrium and Balance01:15

Equilibrium and Balance

The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Diabetes Insipidus II: Pathophysiology01:22

Diabetes Insipidus II: Pathophysiology

Normally, water balance is maintained through three interconnected mechanisms: the hypothalamic thirst center, the synthesis and release of antidiuretic hormone (ADH, or vasopressin), and the kidneys' responsiveness to this hormone. ADH is synthesized in the hypothalamus, released from the posterior pituitary, and acts on the distal nephron, allowing water reabsorption and concentrated urine production.Diabetes Insipidus and Its TypesIn diabetes insipidus (DI), this regulatory system is...
Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...

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Updated: May 17, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
09:09

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Published on: April 11, 2025

Audiovestibular changes in diabetes mellitus.

D R Sharma1, A K Gupta, R K Saxena

  • 1Department of ENT, I.G. Medical College, 171 001 Shimla.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Diabetes mellitus significantly impacts hearing, causing irreversible bilateral, symmetrical high-frequency hearing loss that worsens with disease progression. Vestibular functions remain unaffected, but hearing loss correlates directly with blood sugar levels.

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Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Area of Science:

  • Otorhinolaryngology
  • Endocrinology
  • Audiology

Background:

  • Diabetes mellitus is a systemic disease with potential microvascular complications.
  • Audiovestibular dysfunction is a recognized complication in some chronic diseases.

Purpose of the Study:

  • To evaluate audiovestibular functions in patients with diabetes mellitus.
  • To determine the type and characteristics of hearing loss associated with diabetes mellitus.
  • To assess the impact of diabetes on vestibular function.

Main Methods:

  • Audiovestibular evaluation of 50 patients diagnosed with diabetes mellitus.
  • Assessment included pure-tone audiometry and vestibular function tests.
  • Correlation analysis between hearing loss, disease duration, complications, and glycemic control.

Main Results:

  • Diabetes mellitus was associated with significant bilateral, symmetrical hearing loss, predominantly affecting higher frequencies.
  • Hearing deterioration correlated with disease progression and complications.
  • Hearing loss changes were found to be irreversible even after diabetes control.
  • Vestibular functions showed no significant involvement in the studied diabetic population.
  • A direct correlation was observed between the severity of hearing loss and elevated blood glucose levels.

Conclusions:

  • Diabetes mellitus frequently causes irreversible high-frequency sensorineural hearing loss.
  • Glycemic control is crucial, but hearing loss may not be reversible.
  • Vestibular function appears preserved in diabetes mellitus.
  • Early detection and management of hearing impairment in diabetic patients are recommended.