Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

259
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
259
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

235
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
235
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

193
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
193
Aging01:26

Aging

643
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
643
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.4K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.4K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

3.4K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Landscape of Differentiation Potentials as a "Hallmark" in Oral-derived MSCs.

bioRxiv : the preprint server for biology·2024
Same author

Injectable Tissue-Specific Hydrogel System for Pulp-Dentin Regeneration.

Journal of dental research·2024
Same author

Ayurvedic management of alopecia areata: A case report.

Journal of Ayurveda and integrative medicine·2022
Same author

HIF-1α Stabilization Boosts Pulp Regeneration by Modulating Cell Metabolism.

Journal of dental research·2022
Same author

Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects.

Stem cells international·2018
Same author

Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials.

Journal of translational medicine·2018
Same journal

Correction: Tracheostomy Management in Oral and Oropharyngeal Carcinoma Patients: A Retrospective Study from a Multidisciplinary Protocol Approach.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
Same journal

Correction: Screening of Oropharyngeal Dysphagia, Laryngopharyngeal Reflux and Job Burnout in Adult Patients with Obstructive Sleep Apnea Syndrome.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
Same journal

Correction: Comparison of the Use of Autologous Platelet Rich Plasma with Conventional Method in Myringoplasty.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
Same journal

Correction to: Digital Eye Strain and Dry Nose: an Observational Study on Screen OverUse and Emerging Otorhinolaryngological Symptoms in Young Adults.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
Same journal

Correction: Retrospective Observational Study To Analyse Indications of Cochleostomy and Changing Trends in Use of Cochleostomy for Cochlear Implant Electrode Insertion.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
Same journal

Correction: Sinonasal Clear Cell Carcinoma Masquerading as Recurrent Inverted Papilloma.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026
See all related articles

Related Experiment Video

Updated: Jan 25, 2026

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention
04:32

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention

Published on: December 20, 2024

844

Deafness in paediatric age group.

H Chopra1, M Munjal, S N Gupta

  • 1Dept of ENT Dayanand Medical College & Hospital, Ludhiana, Punjab.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Deafness affects 12.16% of school children in Northern India, primarily due to conductive hearing loss. Common causes include chronic rhinitis, tonsillitis, and adenoiditis, highlighting the need for early intervention.

More Related Videos

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique
11:39

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique

Published on: September 7, 2022

2.6K
Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks
09:04

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

13.3K

Related Experiment Videos

Last Updated: Jan 25, 2026

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention
04:32

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention

Published on: December 20, 2024

844
Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique
11:39

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique

Published on: September 7, 2022

2.6K
Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks
09:04

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

13.3K

Area of Science:

  • Otolaryngology
  • Pediatric Audiology
  • Public Health

Background:

  • Hearing impairment is a significant global health concern.
  • Early identification and management of deafness in children are crucial for development.
  • Prevalence and causes of childhood deafness vary geographically.

Purpose of the Study:

  • To investigate the incidence and primary causes of deafness in neonates, infants, and school-aged children.
  • To analyze the types of hearing loss prevalent in the school-going population.
  • To identify common contributing factors to deafness in Northern India.

Main Methods:

  • A cross-sectional study was conducted on 20 neonates, 100 infants, and 1340 school-aged children.
  • Data was collected by the E.N.T. Department at Dayanand Medical College and Hospital, Ludhiana, Punjab.
  • Audiological assessments and clinical examinations were performed to determine deafness incidence and etiology.

Main Results:

  • The incidence of deafness in the school-going population was recorded as 12.16%.
  • Conductive hearing loss constituted 98% of the cases, while sensorineural (S.N.) loss accounted for 2%.
  • Notable contributing factors included chronic rhinitis, tonsillitis, and adenoiditis.

Conclusions:

  • Childhood deafness, particularly conductive hearing loss, is highly prevalent in the studied region of Northern India.
  • Common upper respiratory tract infections are significant contributors to childhood deafness.
  • Public health initiatives focusing on managing these conditions may reduce the burden of deafness in children.