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Updated: May 17, 2026

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Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
Published on: October 18, 2021
Prognoma of maxilla.
I N Kundu1, A K Saha, S N Ganguh
1Reader Deptt. of E.N.T., N R S Medical College, Calcutta.
Summary
This report details a rare prognoma, a type of melanotic neuroectodermal tumor, found in a young female child affecting the right maxilla. Prognoma is a dysembryogenic tumor of infancy with few documented cases worldwide.
Area of Science:
- Oncology
- Pediatric Pathology
- Developmental Biology
Background:
- Prognoma is an exceptionally rare dysembryogenic tumor originating in infancy.
- The world literature contains very few documented cases of this condition.
- Melanotic neuroectodermal tumors represent the histopathological classification of prognoma.
Purpose of the Study:
- To present a case report of prognoma in a pediatric patient.
- To highlight the clinical presentation and histopathological findings of prognoma.
- To contribute to the limited existing literature on this rare tumor.
Main Methods:
- Case presentation of a female child diagnosed with prognoma.
- Inclusion of histopathological analysis confirming the tumor type.
- Reporting of relevant biochemical markers associated with the case.
Main Results:
- The tumor affected the right maxilla in the presented case.
- Histopathological examination confirmed prognoma as a melanotic neuroectodermal tumor.
- Elevated serum alpha-fetoprotein and urinary vanillylmandelic acid (VMA) levels were noted.
Conclusions:
- This case adds to the scarce global data on prognoma.
- Prognoma should be considered in the differential diagnosis of infantile tumors, particularly those involving the maxilla.
- Further research is warranted to understand the pathogenesis and optimal management of prognoma.
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