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Effect of tonsillectomy on aso-titre

N Viswanathan1, S S Nair, S Thulseedharan

  • 1ENT Medical College, Trivandrum.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed

Insights

This study followed children with chronic tonsillitis after tonsillectomy. Post-surgery, Antistreptolysin O (ASO) titre levels significantly decreased over one year.

Area of Science:

  • Pediatric Otolaryngology
  • Immunology of Infectious Diseases

Background:

  • Chronic tonsillitis affects numerous children globally.
  • Elevated Antistreptolysin O (ASO) titres indicate persistent streptococcal infection or inflammation.
  • Tonsillectomy is a common surgical intervention for chronic tonsillitis.

Purpose of the Study:

  • To evaluate the impact of tonsillectomy on Antistreptolysin O (ASO) titres in children with chronic tonsillitis.
  • To assess the long-term trend of ASO titre reduction following surgical intervention.

Main Methods:

  • Screening of 136 children under 15 with chronic tonsillitis.
  • Selection of 56 patients with ASO titres > 200 IU/ml for tonsillectomy.
  • Serial ASO titre measurements at 1 month, 3 months, 6 months, and 1 year post-tonsillectomy.

Main Results:

  • A significant reduction in ASO titres was observed after tonsillectomy.
  • ASO titres decreased to 62% at 3 months, 78% at 6 months, and 88% at 1 year post-surgery.
  • The study demonstrates a clear downward trend in ASO titres over the follow-up period.

Conclusions:

  • Tonsillectomy is an effective treatment for reducing elevated ASO titres in children with chronic tonsillitis.
  • Surgical intervention aids in resolving underlying streptococcal activity or inflammation.
  • This supports tonsillectomy as a viable option for managing persistent tonsillitis with elevated ASO levels.

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