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Updated: May 17, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Prophylactic budesonide nasal spray after polypectomy.

S K Gulati¹, K Sharma, G Kaur Shergill

¹Department of E.N.T., Govt. Medical College, Amritsar.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|November 3, 2012

Summary

This summary is machine-generated.

Budesonide nasal spray significantly reduced nasal polyp recurrence after surgery compared to placebo. Patients with a history of recurrent nasal polyposis saw greater benefits from this budesonide treatment.

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Area of Science:

Otolaryngology
Pharmacology

Background:

Nasal polyps are common inflammatory growths in the nasal cavity.
Recurrence after surgical removal (polypectomy) is a significant clinical challenge.

Purpose of the Study:

To evaluate the efficacy of budesonide nasal spray in preventing nasal polyp recurrence post-polypectomy.
To compare budesonide nasal spray with placebo in a double-blind study.

Main Methods:

A double-blind, placebo-controlled study involving 63 patients post-polypectomy.
Patients received either budesonide nasal spray or a placebo for 3 months.
Follow-up was conducted over 9 months.

Main Results:

Budesonide treatment resulted in a significantly lower rate of nasal polyp recurrence compared to placebo.
Patients with a history of recurrent nasal polyposis experienced greater benefits from budesonide treatment.

Conclusions:

Budesonide nasal spray is effective in the prophylaxis of nasal polyp recurrence after surgical avulsion.
Topical budesonide offers particular benefit for patients with a history of recurrent nasal polyposis.