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Updated: May 17, 2026

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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Kimura's disease
S R Ranka1, A Rajput, C V Kantharia
1Dept. of Surgery, Seth G. S. Medical College & K. E. M. Hospital, 400 012, MS Mumbai, India.
Summary
Kimura's disease is a rare condition presenting as a painless neck mass in children. Diagnosis requires suspecting the tetrad of symptoms including eosinophilia and specific antibody levels.
Area of Science:
- Pediatric Medicine
- Immunology
- Pathology
Background:
- Kimura's disease is a rare, benign inflammatory condition.
- It typically affects young adults and children, often presenting with a cervical mass.
Purpose of the Study:
- To highlight the diagnostic challenges and key features of Kimura's disease in a pediatric case.
- To present a management flowchart based on literature review.
Main Methods:
- Case report of a 12-year-old child with unilateral cervical mass.
- Initial investigations were inconclusive, with eosinophilia noted.
- Diagnosis confirmed via excision biopsy and retrospective analysis.
Main Results:
- The child presented with a unilateral cervical mass and eosinophilia.
- Excision biopsy confirmed Kimura's disease.
- The study emphasizes the diagnostic tetrad: painless unilateral cervical lymphadenopathy, eosinophilia, hyperimmunoglobulin E, and positive Candida antibodies.
Conclusions:
- Kimura's disease should be considered in pediatric cases with the characteristic tetrad of symptoms.
- Prompt diagnosis and appropriate management are crucial.
- A treatment flowchart aids in managing this condition.
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