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Related Concept Videos

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...

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Related Experiment Video

Updated: May 17, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Kimura's disease.

S R Ranka1, A Rajput, C V Kantharia

  • 1Dept. of Surgery, Seth G. S. Medical College & K. E. M. Hospital, 400 012, MS Mumbai, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Kimura's disease is a rare condition presenting as a painless neck mass in children. Diagnosis requires suspecting the tetrad of symptoms including eosinophilia and specific antibody levels.

Keywords:
Candida specific AntibodiesEosinophiliaKimura’s

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Functional Characterization of Endogenously Expressed Human RYR1 Variants
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Functional Characterization of Endogenously Expressed Human RYR1 Variants

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Last Updated: May 17, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Functional Characterization of Endogenously Expressed Human RYR1 Variants
07:59

Functional Characterization of Endogenously Expressed Human RYR1 Variants

Published on: June 9, 2021

Area of Science:

  • Pediatric Medicine
  • Immunology
  • Pathology

Background:

  • Kimura's disease is a rare, benign inflammatory condition.
  • It typically affects young adults and children, often presenting with a cervical mass.

Purpose of the Study:

  • To highlight the diagnostic challenges and key features of Kimura's disease in a pediatric case.
  • To present a management flowchart based on literature review.

Main Methods:

  • Case report of a 12-year-old child with unilateral cervical mass.
  • Initial investigations were inconclusive, with eosinophilia noted.
  • Diagnosis confirmed via excision biopsy and retrospective analysis.

Main Results:

  • The child presented with a unilateral cervical mass and eosinophilia.
  • Excision biopsy confirmed Kimura's disease.
  • The study emphasizes the diagnostic tetrad: painless unilateral cervical lymphadenopathy, eosinophilia, hyperimmunoglobulin E, and positive Candida antibodies.

Conclusions:

  • Kimura's disease should be considered in pediatric cases with the characteristic tetrad of symptoms.
  • Prompt diagnosis and appropriate management are crucial.
  • A treatment flowchart aids in managing this condition.