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Fungal infections and cavernous sinus thrombosis
152 C Udham Singh Nagar, 141001 Ludhiana.
Summary
Rhino-cerebral mucormycosis is common in uncontrolled diabetics. This study reports two rare cases of cavernous sinus thrombosis caused by fungal infections, detailing their symptoms, signs, and treatment.
Area of Science:
- Ophthalmology
- Neurology
- Infectious Diseases
Background:
- Rhino-cerebral mucormycosis is a serious fungal infection, particularly prevalent in individuals with uncontrolled diabetes mellitus.
- Cavernous sinus thrombosis is a rare but life-threatening complication of fungal sinusitis.
Purpose of the Study:
- To report two cases of rhino-cerebral mucormycosis with fulminant spread to the cavernous sinus.
- To highlight the clinical presentation, diagnostic challenges, and therapeutic strategies for this rare condition.
Main Methods:
- Case report of two patients with rhino-cerebral mucormycosis and cavernous sinus thrombosis.
- Review of clinical symptoms, diagnostic imaging (MRI/CT), and treatment protocols.
Main Results:
- Both patients presented with rapid progression of symptoms, including ophthalmoplegia and neurological deficits.
- Fungal elements confirmed as the cause of cavernous sinus thrombosis.
- Treatment involved a combination of antifungal therapy and surgical/supportive measures.
Conclusions:
- Cavernous sinus thrombosis secondary to rhino-cerebral mucormycosis, though rare, requires prompt recognition and aggressive management.
- Early diagnosis and multidisciplinary treatment are crucial for improving outcomes in these critical cases.
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