Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Toxicity assays and in silico approach to assess the impacts of chlorine dioxide on survival, respiration and some biochemical markers of marine zooplankton.

Marine environmental research·2024

Same author

Surgical outcomes of common arterial trunk repair beyond infancy.

Indian journal of thoracic and cardiovascular surgery·2023

Same author

A method for noninvasive beat-by-beat visualization of His bundle signals.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·2023

Same author

Spectrum of opportunistic fungal lung co-infections in COVID-19: What the radiologist needs to know.

Radiologia·2022

Same author

Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves.

Journal of pediatric urology·2022

Same author

[Spectrum of opportunistic fungal lung co-infections in COVID-19: What the radiologist needs to know].

Radiologia·2022

Same journal

Correction: Tracheostomy Management in Oral and Oropharyngeal Carcinoma Patients: A Retrospective Study from a Multidisciplinary Protocol Approach.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

Same journal

Correction: Screening of Oropharyngeal Dysphagia, Laryngopharyngeal Reflux and Job Burnout in Adult Patients with Obstructive Sleep Apnea Syndrome.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

Same journal

Correction: Comparison of the Use of Autologous Platelet Rich Plasma with Conventional Method in Myringoplasty.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

Same journal

Correction to: Digital Eye Strain and Dry Nose: an Observational Study on Screen OverUse and Emerging Otorhinolaryngological Symptoms in Young Adults.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

Same journal

Correction: Retrospective Observational Study To Analyse Indications of Cochleostomy and Changing Trends in Use of Cochleostomy for Cochlear Implant Electrode Insertion.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

Same journal

Correction: Sinonasal Clear Cell Carcinoma Masquerading as Recurrent Inverted Papilloma.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 17, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Winkler's disease.

Joe Jacob K¹, S Satheesh, P Menon

¹Department of E.N.T., Government Medical College, 686008 Kottayam, Kerala India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|November 3, 2012

Summary

This summary is machine-generated.

Chondrodermatitis nodularis chronica helices (CNHC), or Winkler's disease, causes painful ear nodules in men over 40. Standard treatments like excision or laser vaporization often lead to frequent recurrences.

Keywords:

Carbon dioxide laser Winkler's disease

More Related Videos

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Related Experiment Videos

Last Updated: May 17, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Area of Science:

Dermatology
Otolaryngology

Background:

Chondrodermatitis nodularis chronica helices (CNHC), also known as Winkler's disease, presents as a painful, persistent nodule on the ear helix.
This condition predominantly affects males over 40 years of age.

Purpose of the Study:

To summarize the clinical presentation and standard treatment outcomes for CNHC.

Main Methods:

Review of existing literature on Winkler's disease.
Analysis of standard therapeutic interventions.

Main Results:

CNHC is characterized by an erythematous nodule on the helix of the pinna.
Common treatments include local excision and CO2 laser vaporization.

Conclusions:

Standard treatments for CNHC have a high rate of recurrence.
Further research may be needed to explore more effective, long-term treatment options.