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Related Concept Videos

Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
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Classification of Illness01:17

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Concepts of Health and Illness01:29

Concepts of Health and Illness

Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
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Updated: May 17, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

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Published on: July 21, 2023

Kikuchi - Fujimoto disease.

V Satavahana Chowdary1, E C Vinay Kumar, G Swarna Latha

  • 1Dept. of ENT & Head and Neck Surgery, Dept. of Pathology, Apollo Hospitals, Jubilee Hills, Hyderabad. (A.P).

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary

Kikuchi-Fujimoto disease, a rare cause of cervical adenopathy, typically affects young women. This study reports on three patients who improved without specific treatment, highlighting its benign and self-limiting nature.

Keywords:
Bilateral cervical adenopathyHistiocytic necrotizing lymphadenitisKikuchi — fujimoto disease

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Area of Science:

  • Otolaryngology
  • Pathology
  • Immunology

Background:

  • Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is an uncommon, benign, and self-limiting condition.
  • It primarily affects young women and is characterized by lymphadenopathy, often in the cervical region.
  • Reports of KFD in the ENT literature are rare, necessitating further clinical documentation.

Purpose of the Study:

  • To report clinical cases of Kikuchi-Fujimoto disease.
  • To highlight the rarity of KFD presentations within the ENT field.
  • To document the clinical course and favorable outcome of affected patients.

Main Methods:

  • Case series involving three patients (two females, one male) presenting with specific symptoms.
  • Clinical evaluation including physical examination and routine investigations.
  • Histopathological examination of enlarged cervical lymph nodes to confirm necrotizing lymphadenitis.

Main Results:

  • Patients presented with fever and bilateral, tender, multiple cervical adenopathy, unresponsive to standard treatments.
  • Erythrocyte Sedimentation Rate (ESR) was elevated in routine investigations.
  • Lymph node biopsy confirmed necrotizing lymphadenitis consistent with KFD.

Conclusions:

  • Kikuchi-Fujimoto disease is a benign condition with a favorable prognosis.
  • Patients experienced significant systemic and local improvement without specific interventions.
  • The study underscores the importance of recognizing KFD in the differential diagnosis of cervical lymphadenopathy, even in the absence of typical ENT findings.