Use of mitomycin C in endo-DCR
Soumitra Ghosh1, Amitabha Roychoudhury, B K Roychaudhuri
1Department of ENT and Head - Neck Surgery, Ramakrishna Mission Seva Pratishthan, Vivekananda Institute of Medical Sciences, Kolkata.
Objective:
To evaluate the role of topical Mitomycin C in Endoscopic Dacryocystorhinostomy (DCR), for the prevention of stomal stenosis.
Patients:
Thirty patients undergoing endoscopic DCR for chronic dacryocystitis were studied prospectively. The follow up period was 12 months.
Technique:
PATIENTS were divided into two groups randomly. All of them underwent endoscopic DCR. One group was subjected to topical Mitomycin C application after surgery while the control group was not.
Main Outcome Measures:
Postoperative relief of epiphora and endoscopic documentation of the patency of the stoma were the main outcome measures.
Results:
80% cases of the Mitomycin C group and 86.67% cases of the non Mitomycin C group had long-term successful results. This result is not statistically significant (p> 0.2).
Conclusion:
Intraoperative Mitomycin C application does not alter the long-term results in endoscopic DCR. A properly and adequately performed surgery is more vital for successful result.

