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Related Experiment Video

Updated: May 17, 2026

A Patient-Derived Xenograft Model for Venous Malformation

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

Macroglossia due to venous malformation.

T S Anand¹, Ritu Mittal, T B Shashidhar

¹Department of Otorhinolaryngology and Head and Neck Surgery, Lady Hardinge Medical College, 110001 New Delhi, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|November 3, 2012

Summary

A rare venous malformation of the tongue caused severe functional issues, including obstructive sleep apnea. A combined treatment of sclerotherapy, electrocautery, and radiation therapy effectively managed this extensive vascular malformation.

Keywords:

Electrocautery Macroglossia Radiotherapy Sclerotherapy venous malformation

Related Experiment Videos

Last Updated: May 17, 2026

A Patient-Derived Xenograft Model for Venous Malformation

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

Area of Science:

Vascular Surgery
Otolaryngology
Radiology

Background:

Massive tongue vascular malformations present rare but significant challenges.
These malformations can lead to severe functional impairments affecting speech, eating, and breathing.

Purpose of the Study:

To report a rare case of extensive venous malformation of the tongue.
To detail the functional deficits caused by the malformation.
To describe a multimodality treatment approach.

Main Methods:

A case of extensive tongue venous malformation was treated.
Treatment involved a combination of sclerotherapy, electrocautery, and radiation therapy.

Main Results:

The patient experienced obstructive sleep apnea, inability to speak and eat, and discomfort from dryness and ulceration.
The multimodality treatment approach was employed.

Conclusions:

Extensive tongue venous malformations are rare and cause significant functional impairment.
A combined treatment strategy including sclerotherapy, electrocautery, and radiation therapy can be effective for managing these complex cases.