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Updated: May 17, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
Head and neck squamous cell cancer: Biology (1)
Anupam Mishra1, Amita Pandey, Xiaolin Nong
1Dept of Otolaryngology & HNS, King Gorge Medical University & GM Associated Hospital, Shahmeena Road, Lucknow, 226 003 India.
Abstract:
This review is the first section of tumor biology pertaining to head and neck squamous cell carcinoma (SCCHN). It is intended to introduce the basic concepts of cancer biology to enhance the translational research. The basic tumour biology relates to the aberrations in the normal cell cycle. cell growth and cell death. The genetic aspects of cancer focus upon the roles of oncogenes, tumor suppressor genes and stability genes. The epigenetic mechanisms of the cancer relates to DNA methylation and histone acetylation. This review, discusses the basics of these concepts.
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