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Updated: May 17, 2026

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Published on: March 5, 2019

Adenoid hypertrophy presenting with systemic hypertension.

P Subashini¹, A Ravikumar, M S Ranjit

¹Department of Otolaryngology - Head and Neck Surgery, Sri Ramachandra Medical College and Research Institute (Deemed University), Porur, Chennai, 600 116 Tamilnadu India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|November 3, 2012

Summary

Pediatric obstructive sleep apnea caused by adenoid hypertrophy can lead to severe cardiac issues, including hypertension and heart failure. Adenoidectomy resolved these symptoms, improving the child's cardiac health and eliminating the need for medication.

Keywords:

Adenoid hypertrophy Hypertension Left ventricular dysfunction Obstructive Sleep Apnea (OSA)

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Last Updated: May 17, 2026

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

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Published on: March 5, 2019

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

Area of Science:

Pediatric Cardiology
Otolaryngology
Sleep Medicine

Background:

A pediatric case presented with severe systemic hypertension, left ventricular dysfunction, mitral regurgitation, and congestive cardiac failure.
The patient also exhibited symptoms of obstructive sleep apnea, linked to adenoid hypertrophy.
Current treatments included antihypertensive and anti-failure medications.

Purpose of the Study:

To investigate the impact of adenoidectomy on cardiac dysfunction and obstructive sleep apnea in a pediatric patient.
To assess the potential for medication withdrawal following surgical intervention.

Main Methods:

Clinical examination and diagnosis of adenoid hypertrophy and obstructive sleep apnea.
Medical management of hypertension and congestive cardiac failure.
Surgical intervention via adenoidectomy.

Main Results:

Post-adenoidectomy, obstructive sleep apnea symptoms resolved completely.
Significant improvement in the patient's cardiac status was observed.
The child was successfully weaned off all antihypertensive and anti-failure medications.

Conclusions:

Adenoidectomy is an effective treatment for obstructive sleep apnea in children with associated cardiac dysfunction.
Surgical resolution of upper airway obstruction can lead to marked cardiac improvement and medication independence.