Leiomyosarcoma of larynx: A case report

Area of Science:

• Oncology
• Otorhinolaryngology
• Surgical Pathology

Background:

• Laryngeal leiomyosarcoma is an exceptionally rare malignancy arising from smooth muscle tissue within the larynx.
• Early diagnosis and prompt intervention are crucial for managing this aggressive tumor, often presenting with obstructive symptoms.

Purpose of the Study:

• To report a rare case of laryngeal leiomyosarcoma in a 70-year-old male patient.
• To describe the multidisciplinary management approach and outcomes for this rare laryngeal tumor.

Main Methods:

• The patient presented with acute respiratory distress and stridor, necessitating emergency tracheostomy.
• Subsequent treatment involved a total laryngectomy followed by adjuvant external radiotherapy.
• Clinical and radiological follow-up was conducted for one year post-treatment.

Main Results:

• The patient's emergency condition was stabilized through tracheostomy.
• The total laryngectomy and radiotherapy regimen were completed as planned.
• At one-year follow-up, the patient exhibited no evidence of tumor recurrence.

Conclusions:

• This case highlights the successful management of a rare laryngeal leiomyosarcoma through a combination of surgical resection and radiotherapy.
• Aggressive management can lead to favorable outcomes, even in rare and challenging oncological cases.
• Continued surveillance is essential for patients treated for laryngeal sarcomas.