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Updated: May 17, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Orbital apex syndrome in a child
Vivek Sasindran1, A Ravikumar, Senthil
1Dept of ENT, Head and Neck Surgery, Sri Ramachandra Medical College and Research Institute (DU), Porur, Chennai, 600 116 India.
Orbital apex aspergillosis, a rare fungal infection, can cause severe vision loss and neurological symptoms. Prompt diagnosis and endoscopic removal of infected tissue, followed by voriconazole treatment, led to complete recovery in an 8-year-old boy.
Area of Science:
- Ophthalmology
- Neurology
- Infectious Diseases
Background:
- Orbital apex lesions can present with diverse ophthalmological and neurological symptoms.
- Fungal infections, particularly Aspergillosis, are rare but serious causes of orbital inflammation.
Purpose of the Study:
- To report a case of orbital apex aspergillosis in a pediatric patient.
- To highlight the diagnostic and therapeutic approach for this rare condition.
Main Methods:
- Clinical presentation, ophthalmological, neurological, and radiological examinations were performed.
- Transnasal endoscopic orbital decompression and tissue debridement were utilized.
- Microbiological analysis identified Aspergillus flavus, and treatment with voriconazole was initiated.
Main Results:
- A lesion at the left orbital apex extending into the cavernous sinus was identified.
- Fungal elements of Aspergillus flavus were confirmed through microbiological culture.
- The patient experienced complete symptom resolution following surgical intervention and antifungal therapy.
Conclusions:
- Orbital apex aspergillosis is a treatable condition with a multidisciplinary approach.
- Endoscopic decompression and voriconazole are effective in managing this rare orbital infection.
- Early diagnosis and intervention are crucial for favorable visual and neurological outcomes.
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