Isolated intracranial metastasis from an early glottic cancer: how rare a presentation?

The incidence of distant metastasis with laryngeal tumors varies from 1-4% [1]. The lungs are the most frequent site, followed by bone and liver. Intracranial metastases are rarely clinically diagnosed in head neck cancer patients and if present are mainly located in the cerebrum and cerebellum. Early stage glottic squamous carcinoma with subsequent distant metastasis is rare [2]. We report a patient with T1N0 glottic tumor who underwent a curative radiotherapy and on 3 months follow up presented with isolated intracranial metastasis.