[Peculiarities of epilepsy in women with menstrual dysfunction]

An aim of the study was to optimize the diagnosis and treatment of epilepsy in women of reproductive age with concomitant disturbances of menstrual cycle. One hundred and thirty-two women, aged from 18 to 35 years, were studied. Menstrual dysfunction was found in 47,7% (n = 63): oligomenorrhea--in 68,3% (n = 43), amenorrhea--in 9,5% (n = 6) and dysfunctional metrorrhagia--in 22,2% (n = 14). Based on the character of hormone and ovarian dysfunction, the following syndromes were singled out: polycystic ovaries--54% (n = 34), isolated hypoprogesteronemia--23,8% (n = 15), hypercorticism--14,3% (n = 9), hypogonadotropic hypogonadism--7,9% (n = 5). Different hormonally-active drugs that allowed to normalize the menstrual cycle were used, along with basic antiepileptic drugs, to treat these hormonal dysfunctions and improve the course of epilepsy.