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Copper toxicosis in a Boer goat
Laura C Cregar1, Charles E Wiedmeyer, Davin R Ringen
1Veterinary Medical Diagnostic Laboratory, University of Missouri, Columbia, MO, USA. laura.cregar@mpiresearch.com
Veterinary Clinical Pathology
|November 6, 2012
Summary
Boer goats may be susceptible to copper toxicosis, leading to hemolytic anemia and organ damage. This case highlights the potential for severe health crises in this breed due to copper accumulation.
Area of Science:
- Veterinary Medicine
- Toxicology
- Animal Science
Background:
- Copper toxicosis is a significant concern in livestock, potentially leading to hemolytic crises.
- Boer goats are increasingly recognized as a breed susceptible to copper accumulation and toxicity.
Observation:
- A 1-year-old Boer goat presented with pigmenturia, anorexia, shivering, and progressive hemolytic anemia.
- Clinical signs included Heinz bodies, atypical red blood cells, elevated liver enzymes, hyperbilirubinemia, and azotemia.
Findings:
- Histopathology and ante-mortem hepatic tissue analysis confirmed copper accumulation and hepatocellular necrosis.
- Post-mortem examination revealed hepatic necrosis and hemoglobinuric nephrosis, with markedly increased copper concentrations in liver and kidney.
- No external toxins or mineral imbalances were identified in the water, hay, or goat chow.
Implications:
- This case underscores the predisposition of Boer goats to copper toxicosis, similar to sheep.
- The underlying mechanisms of hepatic copper accumulation and release in Boer goats require further investigation.
- Early recognition and understanding of copper toxicosis are crucial for managing hemolytic crises in susceptible goat breeds.
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