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Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
Ototoxicity in dogs and cats
Naoki Oishi1, Andra E Talaska, Jochen Schacht
1Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, MI 48109-5616, USA.
The Veterinary Clinics of North America. Small Animal Practice
|November 6, 2012
Summary
Veterinary drugs can cause hearing and balance problems in animals. Research on ototoxicity in dogs and cats is limited, but findings in other species offer insights for veterinary chemotherapy complications.
Area of Science:
- Veterinary Medicine
- Toxicology
- Pharmacology
Background:
- Numerous drugs used in veterinary medicine carry risks of ototoxicity, potentially affecting hearing and balance.
- While extensive research exists on ototoxicity in humans and experimental animals, data specific to domestic dogs and cats remains scarce.
- Understanding drug-induced sensory damage is crucial for animal health and welfare.
Purpose of the Study:
- To highlight the potential for ototoxicity from veterinary drugs.
- To bridge the knowledge gap regarding ototoxicity in dogs and cats.
- To provide veterinarians with information on potential chemotherapy-related complications.
Main Methods:
- Literature review of ototoxicity studies in various species.
- Extrapolation of findings from human and experimental animal models.
- Analysis of drug side effect profiles in veterinary medicine.
Main Results:
- Ototoxicity is a recognized adverse effect of various medications.
- Limited specific data available for canine and feline ototoxicity.
- Cross-species similarities in drug-induced ototoxicity are probable.
Conclusions:
- Veterinarians should be aware of potential hearing and balance issues associated with drug administration.
- Further research is needed to fully characterize ototoxicity risks in dogs and cats.
- Knowledge from other species can guide the management of potential drug-induced sensory deficits in veterinary patients.
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