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Updated: May 17, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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Stratification of postprostatectomy urinary function using expanded prostate cancer index composite.

Jonathan S Ellison1, Chang He, David P Wood

  • 1Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA. jonellis@med.umich.edu

Urology
|November 6, 2012
PubMed
Summary
This summary is machine-generated.

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New categories for the Expanded Prostate Cancer Index Composite-Urinary (EPIC-UIN) scores classify post-prostatectomy urinary incontinence. These functional categories help assess recovery and guide patient care after prostate cancer treatment.

Area of Science:

  • Urology
  • Oncology
  • Health-related Quality of Life Research

Background:

  • Prostate cancer treatment, particularly prostatectomy, often leads to urinary incontinence.
  • Assessing the severity and recovery of urinary function is crucial for patient well-being.
  • Validated instruments like the Expanded Prostate Cancer Index Composite-Urinary (EPIC-UIN) are used to measure this quality of life aspect.

Purpose of the Study:

  • To classify Expanded Prostate Cancer Index Composite-Short Form urinary domain (EPIC-UIN) scores into clinically meaningful categories.
  • To establish functional categories for assessing urinary incontinence after prostate cancer treatment.
  • To correlate EPIC-UIN scores with the Incontinence Severity Index (ISI) for improved interpretation.

Main Methods:

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  • Retrospective review of a prospectively maintained database of patients undergoing prostatectomy.
  • Analysis of patient and tumor factors, alongside validated instruments: EPIC-UIN and Incontinence Severity Index (ISI).
  • Statistical analysis to determine cutpoints for EPIC-UIN scores correlating with ISI severity levels (mild, moderate, severe).

    • Main Results:

    • 446 patients and 764 questionnaires were analyzed; average age 59.2 years, Gleason score 6.75.
    • Defined EPIC-UIN score ranges: 0-49 (severe), 50-69 (moderate), 70-100 (mild) incontinence.
    • High agreement (74.1%, kappa 0.6541) between EPIC-UIN categories and ISI scores, with good sensitivity and specificity for severe and moderate incontinence.

    Conclusions:

    • Developed categorical EPIC-UIN groups representing mild, moderate, and severe urinary incontinence.
    • These categories offer meaningful guidance for assessing postoperative urinary incontinence.
    • The classification aids in evaluating the recovery of urinary function following prostate cancer treatment.