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An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay
Published on: January 26, 2019
Selection of a screening panel of rhinoviral serotypes
Nick Tomkinson1, Mark Wenlock, Christopher McCrae
1AstraZeneca R&D Alderley Park, Cheshire SK10 4TF, UK. nick.tomkinson@astrazeneca.com
Bioorganic & Medicinal Chemistry Letters
|November 6, 2012
Abstract:
A novel methodology for the selection of a representative primary and secondary screening panel of rhinoviral serotypes for the purposes of identifying potential antiviral agents is presented. This methodology focuses on the active-sites of the rhinoviral proteins but does not invoke historical SAR data, thereby avoiding compound bias.

