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Inaugural severe vaso-occlusive retinopathy in systemic lupus erythematosus
Audrey Giocanti-Auregan1, Typhaine Grenet, Charlotte Rohart
1Department of Ophthalmology, Avicenne Hospital, 125 Rue de Stalingrad, 93000, Bobigny, France. audreygiocanti@yahoo.fr
International Ophthalmology
|November 6, 2012
Summary
Systemic lupus erythematosus (SLE) can cause severe vision loss through vaso-occlusive retinopathy. This case highlights vision impairment as an initial symptom of SLE, even in young, healthy individuals.
Area of Science:
- Ophthalmology
- Rheumatology
- Systemic Lupus Erythematosus
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
- Ocular involvement in SLE can range from mild to severe, impacting visual function.
- Vaso-occlusive retinopathy is a recognized but less common complication of SLE.
Observation:
- A 26-year-old African male presented with meningo-encephalitic syndrome and severe bilateral visual impairment.
- Fundus examination revealed extensive retinal vascular occlusions.
- Fluorescein angiography demonstrated bilateral retinal and choroidal ischemia.
Findings:
- The patient was diagnosed with systemic lupus erythematosus based on neurological, pleuritic, renal, and hematologic disorders.
- Severe bilateral vaso-occlusive retinopathy was identified as the inaugural manifestation of SLE.
- Significant visual loss occurred as the presenting symptom.
Implications:
- This case underscores the potential for severe ocular manifestations, including vaso-occlusive retinopathy, as the initial presentation of SLE.
- Central nervous system involvement in SLE may be more prevalent in patients with significant retinal changes.
- Early recognition of ocular symptoms is crucial for timely diagnosis and management of SLE.
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