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Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20

Yi Jin1, Matthew J Cliff, Nicola J Baxter

  • 1Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, S10 2TN, UK.

Angewandte Chemie (International Ed. in English)
|November 6, 2012
PubMed
Abstract

No abstract available in PubMed .

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Proteins undergo chemical modifications that trigger changes in the charge, structure, and conformation of the proteins. Phosphorylation, acetylation, glycosylation, nitrosylation, ubiquitination, lipidation, methylation, and proteolysis are various protein modifications that regulate protein activity. Such modifications are usually enzyme-driven.
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