3-Methyl-amino-3-phenyl-propan-1-ol

Area of Science:

• Crystallography
• Organic Chemistry
• Materials Science

Background:

• Amino alcohols are versatile organic compounds with applications in pharmaceuticals and materials.
• Understanding the solid-state structure of amino alcohols is crucial for predicting their physical properties and reactivity.
• The specific compound C10H15NO was investigated for its unique structural features.

Purpose of the Study:

• To elucidate the crystal structure of the amino alcohol C10H15NO.
• To identify intermolecular interactions, such as hydrogen bonding, in the crystal lattice.
• To characterize the self-assembly behavior of the molecules in the solid state.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
• Analysis of hydrogen bonding networks and their topological descriptors (e.g., R(2)(2)(12), R(4)(4)(8)).
• Computational methods may be used to complement experimental findings (if applicable, though not explicitly stated in the abstract).

Main Results:

• The compound C10H15NO was confirmed as an amino alcohol with a terminal hydroxyl group.
• A nearly planar arrangement of non-hydrogen atoms, excluding the hydroxyl and phenyl groups, was observed.
• Molecules self-assemble into centrosymmetric dimers and tetrameric units through classical O-H⋯N and N-H⋯O hydrogen bonds.
• These hydrogen bonds form characteristic ring motifs, leading to a robust three-dimensional network.

Conclusions:

• The crystal structure of C10H15NO reveals specific hydrogen bonding patterns that dictate its solid-state organization.
• The formation of dimers and tetramers through hydrogen bonds is a key feature of its self-assembly.
• The resulting 3D network highlights the importance of intermolecular forces in constructing crystalline materials from amino alcohols.