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Published on: August 16, 2018
3-(2-Chloro-3-hy-droxy-4-meth-oxy-phen-yl)-1-(4,5-dimeth-oxy-2-methyl-phen-yl)prop-2-en-1-one
U H Patel1, S A Gandhi, V M Barot
1Department of Physics, Sardar Patel University, Vallabh Vidya Nagar, Gujarat 388 120, India.
Acta Crystallographica. Section E, Structure Reports Online
|November 6, 2012
Summary
This study details a chloro-chalcone derivative, revealing its unique molecular structure and crystal packing. The research highlights intramolecular hydrogen bonding and intermolecular interactions influencing its solid-state arrangement.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Chalcones are a biologically significant class of compounds.
- Understanding the structural properties of chalcone derivatives is crucial for their applications.
Purpose of the Study:
- To characterize the crystal structure of a novel chloro-chalcone derivative.
- To investigate the intermolecular interactions and hydrogen bonding in the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of graph-set motifs and hydrogen bonding interactions.
Main Results:
- The compound C(19)H(19)ClO(5) exhibits a significant twist (55.33°) between its benzene rings.
- An intramolecular C-H⋯Cl hydrogen bond forms an S(5) motif.
- Bifurcated O-H⋯(O,O) hydrogen bonds create zigzag chains along the c-axis.
- Weak π-π and C-H⋯π interactions were also observed.
Conclusions:
- The crystal structure reveals specific hydrogen bonding patterns and π-π interactions.
- These interactions dictate the solid-state packing and potential properties of the chloro-chalcone derivative.
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