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Published on: June 15, 2019
Management and Treatment Guidelines for Sepsis in Pediatric Patients
Nidal El-Wiher1, Timothy T Cornell, Nranjany Kissoon
1Division of Critical Care Medicine, C.S. Mott Children's Hospital at the University of Michigan, Ann Arbor, MI.
Abstract:
Sepsis remains one of the leading causes of morbidity and mortality in children despite improved understanding of the pathophysiology leading to better clinical management and survival. Recent studies have identified several areas that must be addressed by the clinician in order to continue to impact the morbidity and mortality associated with sepsis. In this review, we discuss the evidence in several of these areas including initial resuscitation, pathogen eradication, maintenance of oxygen delivery, and directed modifiers of the inflammatory response. Our overall goal is to provide the bedside clinician with an updated systematic approach to treat sepsis in children.
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