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Knowledge, attitude and perception/practices (KAP) of medical practitioners in India towards adverse drug reaction

Mala Kharkar1, Suresh Bowalekar

  • 1Vice Principal, Patkar and Varde College, B2-12, Mahindra Gardens, S.V.Road, Goregaon(west) Mumbai, India.

Perspectives in Clinical Research
|November 6, 2012
PubMed
Abstract

Insights

Medical practitioners in India show good knowledge and perception of Adverse Drug Reaction (ADR) reporting, but actual reporting practices are low. Despite awareness, only 18.5% reported ADRs to government centers, indicating a gap between knowledge and practice.

Area of Science:

  • Pharmacovigilance
  • Clinical Research
  • Public Health

Background:

  • Adverse Drug Reactions (ADRs) pose a significant risk to patient safety.
  • Effective pharmacovigilance relies on timely and accurate ADR reporting by healthcare professionals.
  • Understanding the knowledge, attitude, and practices (KAP) of medical practitioners is crucial for improving ADR reporting systems in India.

Purpose of the Study:

  • To assess the knowledge, attitude, and practices (KAP) of medical practitioners (MPs) in India regarding Adverse Drug Reaction (ADR) reporting.
  • To identify barriers and facilitators influencing ADR reporting among Indian physicians.
  • To provide insights for enhancing pharmacovigilance activities in the Indian healthcare system.

Main Methods:

  • A cross-sectional study was conducted using a questionnaire-based survey.
  • The study involved 1200 randomly selected medical practitioners across different zones in India.
  • Data analysis focused on assessing awareness, familiarity with reporting procedures, and actual reporting behaviors.

Main Results:

  • A response rate of 73% (870 out of 1200) was achieved.
  • While 47.5% were aware of government ADR centers and 59.2% knew the reporting procedure, only 18.5% had reported ADRs to these centers.
  • Conversely, 87.9% reported ADRs to pharmaceutical company representatives or NGOs, and 80.5% agreed on the importance of safety, with 96% finding ADR centers useful.

Conclusions:

  • Indian medical practitioners possess adequate knowledge and positive perceptions regarding ADR reporting.
  • A significant discrepancy exists between the perceived importance of ADR reporting and the actual practice, with low reporting rates to official government channels.
  • Interventions are needed to bridge the gap between knowledge/attitude and practice to improve pharmacovigilance in India.
Keywords:
ADR reportingAdverse drug reactionspharmacovigilance

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