Related Experiment Video
Updated: May 17, 2026
09:47
Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
[A local gingival swelling which was based on a peripheral giant cell lesion]
N Zwier1, J E van der Wal, F K L Spijkervet
1Afdeling Mondziekten, Kaak- en Aangezichtschirurgie, Universitair Medisch Centrum Groningen.
Nederlands Tijdschrift Voor Tandheelkunde
|November 7, 2012
Summary
A peripheral giant cell lesion presented as a gingival swelling that bled during brushing. Surgical removal with thorough bone curettage is crucial to prevent recurrence of this benign oral lesion.
Area of Science:
- Oral pathology
- Dentistry
- Surgical oncology
Background:
- Gingival swellings can present with various etiologies, necessitating accurate differential diagnosis.
- Peripheral giant cell lesions (PGCL) are benign reactive lesions of the oral cavity.
Observation:
- A 29-year-old woman presented with a year-long history of a localized gingival swelling.
- The lesion bled during tooth brushing, prompting dental consultation.
Findings:
- Differential diagnoses included epulis gravidarum, PGCL, and peripheral ossifying granuloma.
- Histopathological examination confirmed the diagnosis of a peripheral giant cell lesion following surgical excision.
Implications:
- Thorough surgical removal, including excochleation of the underlying bone, is essential for PGCL management.
- Complete removal significantly reduces the likelihood of lesion recurrence.
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