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Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
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[From karyotype to genome wide selection (GWS) sequencing in Burkitt lymphoma]

Alain Bernheim1, Saloua Toujani, Philippe Dessen

  • 1U985 Inserm, pathologie moléculaire, institut de cancérologie Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif, France. bernheim@igr.fr

Annales De Pathologie
|November 7, 2012
PubMed
Abstract

No abstract available in PubMed .

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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