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Related Experiment Videos

Suicidal ideation in Darier's disease.

K D Denicoff1, Z A Lehman, D R Rubinow

  • 1Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892.

Journal of the American Academy of Dermatology
|February 1, 1990
PubMed
Summary

Patients with severe Darier's disease show higher rates of suicidal thoughts and plans compared to other severe skin conditions. This highlights the significant psychological impact of chronic, disfiguring dermatological disorders.

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Area of Science:

  • Dermatology
  • Psychiatry
  • Psychosomatic Medicine

Background:

  • Darier's disease is a rare genetic skin disorder causing significant physical and psychological distress.
  • Patients with chronic and disfiguring skin conditions often experience comorbid psychiatric issues.

Purpose of the Study:

  • To investigate the prevalence of suicidal ideation and behavior in patients with severe Darier's disease.
  • To compare psychiatric histories, specifically suicidal ideation, between patients with Darier's disease and a control group with other severe keratinization disorders.

Main Methods:

  • A case-control study design was employed.
  • The study included patients diagnosed with severe Darier's disease and a control group with comparably severe dermatologic disorders of keratinization.

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  • Psychiatric histories, focusing on suicidal thoughts and attempts, were collected and compared between the groups.

    • Main Results:

    • Seven out of eleven patients with severe Darier's disease reported a history of suicidal thoughts.
    • Three patients with Darier's disease reported either a suicide attempt or a specific suicide plan.
    • Compared to the control group, patients with Darier's disease exhibited a higher incidence of suicidal ideation.

    Conclusions:

    • Suicidal ideation is a significant concern for individuals with severe Darier's disease.
    • Chronic and disfiguring cutaneous disorders, such as Darier's disease, are associated with an increased risk of suicidal ideation.
    • Psychiatric screening and support are crucial for patients managing severe dermatological conditions.