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Updated: May 17, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Laser in situ keratomileusis using optimized aspheric profiles and cyclotorsion control to treat compound myopic
Jorge L Alió1, Ana B Plaza-Puche1, Lorena M Martinez1
1From the Vissum Corporation (Alió, Plaza-Puche, Martinez, Torky, Brenner) and the Division of Ophthalmology (Alió), Universidad Miguel Hernández, Alicante, Spain; Mansoura University (Torky), Mansoura, Egypt.
Purpose:
To evaluate the visual outcomes after laser in situ keratomileusis (LASIK) surgery to correct primary compound myopic astigmatism with high cylinder performed using a fast-repetition-rate excimer laser platform with optimized aspheric profiles and cyclotorsion control.
Setting:
Vissum Corporation and Division of Ophthalmology, Universidad Miguel Hernández, Alicante, Spain.
Design:
Retrospective consecutive observational nonrandomized noncomparative case series.
Methods:
Eyes with primary compound myopic astigmatism and a cylinder power over 3.00 diopters (D) had uneventful LASIK with femtosecond flap creation and fast-repetition-rate excimer laser ablation with aspheric profiles and cyclotorsion control. Visual, refractive, and aberrometric outcomes were evaluated at the 6-month follow-up. The astigmatic correction was evaluated using the Alpins method and Assort software.
Results:
The study enrolled 37 eyes (29 patients; age range 19 to 55 years). The significant reduction in refractive sphere and cylinder 3 months and 6 months postoperatively (P<.01) was associated with improved uncorrected distance visual acuity (P<.01). Eighty-seven percent of eyes had a spherical equivalent within ±0.50 D; 7.5% of eyes were retreated. There was no significant induction of higher-order aberrations (HOAs). The targeted and surgically induced astigmatism magnitudes were 3.23 D and 2.96 D, respectively, and the correction index was 0.91. The safety and efficacy indices were 1.05 and 0.95, respectively.
Conclusions:
Laser in situ keratomileusis for primary compound myopic astigmatism with high cylinder (>3.00 D) performed using a fast-repetition-rate excimer laser with optimized aspheric profiles and cyclotorsion control was safe, effective, and predictable and did not cause significant induction of HOAs.
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