Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 17, 2026

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

Mapping cortical dynamics using simultaneous MEG/EEG and anatomically-constrained minimum-norm estimates: an auditory

Adrian K C Lee1, Eric Larson, Ross K Maddox

  • 1Department of Speech & Hearing Sciences, Institute for Learning and Brain Sciences, University of Washington, USA. akclee@uw.edu

Journal of Visualized Experiments : Jove
|November 7, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Addition of CAD polygenic risk score to coronary artery calcium score enhances prediction of MACE.

Frontiers in cardiovascular medicine·2026
Same author

Bone-Conducted Responses Using the Parallel Auditory Brainstem Response Paradigm.

Ear and hearing·2026
Same author

Attention to Pseudotone Melodies Enhances Cortical But Not Brainstem Responses in Humans.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Attention to Psuedo-Tone Melodies Enhances Cortical but Not Brainstem Responses in Humans.

bioRxiv : the preprint server for biology·2025
Same author

Chimeric Music Reveals an Interaction of Pitch and Time in Electrophysiological Signatures of Music Encoding.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025
Same author

The parallel auditory brainstem response paradigm provides accurate and fast hearing thresholds in a clinic-like setting.

medRxiv : the preprint server for health sciences·2025

Magneto- and electroencephalography (MEG/EEG) combined with MRI and minimum-norm estimates (MNE) enable distributed source analysis for brain networks. This method visualizes cortical activity, offering insights into complex cognitive tasks beyond traditional sensor-level analysis.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Biophysics

Background:

  • Magneto- and electroencephalography (MEG/EEG) offer high temporal resolution for studying dynamic brain networks.
  • Traditional sensor-level analysis often focuses on time-locked activity, potentially missing sustained or distributed neural responses.
  • Investigating complex tasks like auditory attention requires methods that capture distributed cortical activity.

Purpose of the Study:

  • To describe a procedure for distributed source analysis using MEG/EEG data combined with individual anatomical MRI.
  • To establish a relationship between sensor data and cortical dipole activation via minimum-norm estimates (MNE).
  • To enable the visualization of distributed brain activity ('brain movies') for group-level analysis.

Main Methods:

More Related Videos

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control
09:37

Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control

Published on: July 5, 2015

Related Experiment Videos

Last Updated: May 17, 2026

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control
09:37

Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control

Published on: July 5, 2015

  • Utilizing individual anatomical MRI to create a forward model relating cortical sources to MEG/EEG sensor data.
  • Employing minimum-norm estimates (MNE) for inverse imaging and distributed source analysis.
  • Denoising sensor data and mapping MEG/EEG activity onto cortical space using FreeSurfer and MNE software.

Main Results:

  • A procedure for generating time-series of cortical dipole activation ('brain movies') from MEG/EEG data.
  • The method effectively maps distributed neural activity across the brain surface.
  • Facilitation of statistical inference and group-level analysis on a common cortical coordinate space.

Conclusions:

  • The described MNE-based inverse imaging approach provides a powerful tool for distributed source analysis in MEG/EEG research.
  • This technique enhances the investigation of sustained and distributed cortical networks involved in cognitive tasks.
  • The freely available software (FreeSurfer, MNE) promotes accessibility for advanced neuroimaging analysis.