Related Experiment Video
Updated: May 17, 2026

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
Published on: July 7, 2023
Right lower-quadrant pain-more than one diagnosis
Cena Tejani1, Tej Phatak, Adam Sivitz
1Emergency Medicine Education, Newark Beth Israel Hospital, Brookly, NY, USA. ctejani5@yahoo.com
Right-lower-quadrant pain can mimic appendicitis. An appendiceal wall hematoma in a child with von Willebrand disease mimicked intussusception on ultrasound, highlighting the need for advanced imaging in complex cases.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Imaging
- Hematology
Background:
- Right-lower-quadrant pain is a common emergency room presentation with a broad differential diagnosis, including appendicitis.
- Von Willebrand disease is a congenital bleeding disorder that can predispose patients to bleeding complications.
Observation:
- An 8-year-old girl with known von Willebrand disease presented with acute right-lower-quadrant pain.
- Initial abdominal ultrasound revealed findings suggestive of intussusception, specifically a "target sign" due to a thickened abdominal wall.
Findings:
- The patient was diagnosed with an appendiceal wall hematoma, a rare complication.
- The appendiceal wall hematoma mimicked the ultrasound appearance of intussusception, demonstrating a potential diagnostic pitfall.
Implications:
- This case underscores the importance of considering rare diagnoses in patients with bleeding disorders presenting with abdominal pain.
- It highlights the limitations of ultrasound in differentiating certain abdominal pathologies and suggests that advanced imaging modalities may be necessary.
- Accurate diagnosis is crucial for appropriate management and to avoid unnecessary interventions.
Related Concept Videos
Abdominal Regions and Quadrants
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four quadrants...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pancreatitis II: Clinical Manifestations and Management

