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MR imaging of early fibrodysplasia ossificans progressiva
K H Caron1, M A DiPietro, A M Aisen
1Department of Radiology, University of Michigan Hospitals, Ann Arbor.
Journal of Computer Assisted Tomography
|March 1, 1990
Abstract:
Fibrodysplasia ossificans progressiva is a rare disorder characterized by progressive heterotopic bone formation in connective tissue and muscle in association with congenital skeletal anomalies. The disease usually leads to extensive immobility and eventual disability. We report the magnetic resonance findings in a boy prior to ossification of his soft tissue masses.
Insights
Fibrodysplasia ossificans progressiva causes abnormal bone growth in soft tissues, leading to immobility. Magnetic resonance imaging revealed early signs in a young patient before significant ossification occurred.
Area of Science:
- Medical imaging and diagnostics
- Rare genetic disorders
- Musculoskeletal system research
Background:
- Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder.
- Characterized by progressive heterotopic ossification in soft tissues and muscles.
- Often associated with congenital skeletal malformations, leading to severe disability.