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Updated: May 17, 2026

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
Published on: November 28, 2012
Radiation-induced eye lens changes and risk for cataract in interventional cardiology
O Ciraj-Bjelac1, M Rehani, A Minamoto
1Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
Background:
Recent studies have reported a significant increase in eye lens opacities among staff in the cardiac catheterization laboratory but indicated further studies are needed to confirm the findings.
Objective:
To evaluate the prevalence of opacities in eyes of cardiologists, radiographers and nurses working in interventional cardiology.
Methods:
The eyes of 52 staff in interventional cardiology facilities and 34 age- and sex-matched unexposed controls were screened in a cardiology conference held in Kuala Lumpur by dilated slit-lamp examination, and posterior lens changes were graded. Individual cumulative lens X-ray exposures were calculated from responses to a questionnaire in terms of workload and working practice.
Results:
The prevalence of posterior lens opacities among interventional cardiologists was 53%, while in nurses and radiographers it was 45%. Corresponding relative risks were 2.6 (95% CI: 1.2-5.4) and 2.2 (95% CI: 0.98-4.9), for interventional cardiologists and support staff, respectively.
Conclusions:
This study confirms a statistically significant increase in radiation-associated posterior lens changes in the eyes of interventional cardiology staff.
